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 Gracias al uso de células madres de ratones, un equipo de investigación, cultivó el primer tejido cutáneo cultivado en laboratorio con folículos pilosos, que puede servir para probar medicamentos, entender mejor el crecimiento del cabello y reducir los ensayos con animales. Ese modelo de piel es más parecido al vello natural que los logrados hasta el momento, según un estudio que publica la revista Cell Reports. Hasta el momento ya existen varios métodos de generar piel con folículos pilosos, pero su capacidad de imitar a la piel real es limitada, pues mientras ésta consta de 20 o más tipos de células la procedente de esos modelos sólo contiene cinco o seis. Investigadores de la Universidad de Medicina de Indiana (EEUU), dirigidos por Karl Koehler, comenzaron usando células madre pluripontenciales (capaces de dar origen a cualquier tipo de tejido) para crear pequeños órganos in vitro que reprodujesen en oído interno. Sin embargo, descubrieron que además de tejido del oído interno estaban generando células cutáneas, por lo que su trabajo se centró en transformar las células en folículos piloso útiles. La investigación demostró que un solo organoide cutáneo desarrollado en cultivo puede producir tanto epidermis como dermis, las dos capas superior e inferior de la piel.
 
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 Gracias al uso de células madres de ratones, un equipo de investigación, cultivó el primer tejido cutáneo cultivado en laboratorio con folículos pilosos, que puede servir para probar medicamentos, entender mejor el crecimiento del cabello y reducir los ensayos con animales. Ese modelo de piel es más parecido al vello natural que los logrados hasta el momento, según un estudio que publica la revista Cell Reports. Hasta el momento ya existen varios métodos de generar piel con folículos pilosos, pero su capacidad de imitar a la piel real es limitada, pues mientras ésta consta de 20 o más tipos de células la procedente de esos modelos sólo contiene cinco o seis. Investigadores de la Universidad de Medicina de Indiana (EEUU), dirigidos por Karl Koehler, comenzaron usando células madre pluripontenciales (capaces de dar origen a cualquier tipo de tejido) para crear pequeños órganos in vitro que reprodujesen en oído interno. Sin embargo, descubrieron que además de tejido del oído interno estaban generando células cutáneas, por lo que su trabajo se centró en transformar las células en folículos piloso útiles. La investigación demostró que un solo organoide cutáneo desarrollado en cultivo puede producir tanto epidermis como dermis, las dos capas superior e inferior de la piel.
 
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